Request

Under the Freedom of Information Act 2000 I’m requesting the following information on prescribing of inclisiran in England:

The number of patients who have been prescribed inclisiran between September 2021 and September 2023, broken down by month.

Further to my FOI request below, can I also have the total number of patients who have been prescribed inclisiran between September 2021 and September 2023?

On 18 September 2023 you clarified the following:

• The latest month in which data is currently available for this request will be June 2023.

Would you like us to provide data between September 2021-June 2023? Alternatively, you could request a different time period or raise this request when the data is available.

• Yes, please can you provide monthly data between September 2021-June 2023. Can you also provide the total number of patients who have been prescribed inclisiran during that time.

Response

A copy of the information is attached.

Total number of unique patients prescribed Inclisiran (including prescribing of the equivalent brand Leqvio) in England regardless of where dispensed in the community for September 2021 to July 2023 both monthly and accumulated.

NHS Prescription Services process prescriptions for Pharmacy Contractors, Appliance Contractors, Dispensing Doctors and Personal Administration with information then used to make payments to pharmacists and appliance contractors in England for prescriptions dispensed in primary care settings (other arrangements are in place for making payments to Dispensing Doctors and Personal Administration). This involves processing over 1 billion prescription items and payments totalling over £9 billion each year. The information gathered from this process is then used to provide information on costs and trends in prescribing in England and Wales to over 25,000 registered NHS and Department of Health and Social Care users.

Data Source: ePACT2

Data in ePACT2 is sourced from the NHSBSA Data Warehouse and is derived from products prescribed on prescriptions and dispensed in the Community. The data captured from prescription processing is used to calculate reimbursement and remuneration. It includes items prescribed in England, Wales, Scotland, Northern Ireland, Guernsey / Alderney, Jersey and Isle of Man which have been dispensed in the community in England. English prescribing that has been dispensed in Wales, Scotland, Guernsey / Alderney, Jersey and Isle of Man is also included.

The Data excludes: • Items not dispensed, disallowed and those returned to the contractor for further clarification. • Prescriptions prescribed and dispensed in Prisons, Hospitals and Private prescriptions. • Items prescribed but not presented for dispensing or not submitted to NHS Prescription Services by the dispenser.

Time Period

September 2021 to July 2023 (monthly – part 1 and accumulated – part 2) Please note there was no data for September 2021 and July 2023 is the latest data available.

Organisation Data:

The data is for prescriptions prescribed in England regardless of where dispensed in the community.

This Dataset:

This dataset is limited to the number of unique patients prescribed Inclisiran and / or equivalent brand Leqvio.

Patient Identification

Where patient identifiable figures have been reported they are based on the information captured during the prescription processing activities. Please note, patient details cannot be captured from every prescription form and based on the criteria used for this analysis, patient information (NHS number) was available for 96.85% of prescription items.

The patient count figures are based on a distinct count of NHS number as captured from the prescription image.

The figures for the number of identifiable patients should not be combined and reported at any other level than provided as this may result in the double-counting of patients. For example, a single patient could appear in the results for multiple months.

Please note that this request and our response is published on our Freedom of Information disclosure log at:

https://opendata.nhsbsa.net/dataset/foi-01414